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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATXN3
All Species:
34.24
Human Site:
S236
Identified Species:
57.95
UniProt:
P54252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54252
NP_001121168.1
364
41781
S236
L
Q
R
A
L
A
L
S
R
Q
E
I
D
M
E
Chimpanzee
Pan troglodytes
XP_001146724
368
42242
S236
L
Q
R
A
L
A
L
S
R
Q
E
I
D
M
E
Rhesus Macaque
Macaca mulatta
XP_001116022
352
40079
S228
L
Q
R
A
L
A
L
S
R
Q
E
I
D
M
E
Dog
Lupus familis
XP_537352
301
34778
A197
K
L
I
G
E
E
L
A
Q
L
K
E
Q
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVD2
355
40515
S236
L
Q
R
A
L
A
I
S
R
Q
E
I
D
M
E
Rat
Rattus norvegicus
O35815
355
40428
S236
L
Q
R
A
L
A
M
S
R
Q
E
I
D
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507271
358
40934
S239
L
Q
K
A
L
A
L
S
R
Q
E
I
D
M
E
Chicken
Gallus gallus
Q9W689
363
41590
S239
F
Q
R
A
L
A
L
S
R
Q
E
I
D
M
E
Frog
Xenopus laevis
NP_001085659
316
35907
S199
L
Q
K
A
L
A
L
S
R
Q
Q
I
D
M
E
Zebra Danio
Brachydanio rerio
NP_957398
266
30028
E162
M
S
A
P
H
A
S
E
T
T
H
T
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623341
340
38556
K218
F
T
R
A
L
S
N
K
E
K
I
S
T
S
K
Nematode Worm
Caenorhab. elegans
O17850
317
35845
G206
T
K
F
F
N
T
V
G
K
R
L
G
G
G
S
Sea Urchin
Strong. purpuratus
XP_786733
388
42119
S267
L
Q
A
A
I
Q
L
S
L
R
G
T
E
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M391
280
30674
F176
I
F
I
V
K
G
N
F
P
Q
E
C
P
M
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
88.7
79.1
N.A.
80.2
80.4
N.A.
78
70.5
52.2
50.5
N.A.
N.A.
42.8
31.3
38.4
Protein Similarity:
100
97.8
90.1
80.7
N.A.
85.4
85.7
N.A.
85.1
79.9
64.8
61.8
N.A.
N.A.
59.6
48.6
56.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
13.3
N.A.
N.A.
20
0
33.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
93.3
100
20
N.A.
N.A.
40
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
72
0
65
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% D
% Glu:
0
0
0
0
8
8
0
8
8
0
58
8
8
8
65
% E
% Phe:
15
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
0
8
8
8
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
15
0
8
0
8
0
0
0
8
58
0
0
0
% I
% Lys:
8
8
15
0
8
0
0
8
8
8
8
0
0
0
8
% K
% Leu:
58
8
0
0
65
0
58
0
8
8
8
0
0
0
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
65
0
% M
% Asn:
0
0
0
0
8
0
15
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% P
% Gln:
0
65
0
0
0
8
0
0
8
65
8
0
8
0
8
% Q
% Arg:
0
0
50
0
0
0
0
0
58
15
0
0
0
8
0
% R
% Ser:
0
8
0
0
0
8
8
65
0
0
0
8
0
8
15
% S
% Thr:
8
8
0
0
0
8
0
0
8
8
0
15
8
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _